Relating individual differences in white matter pathways to children’s arithmetic fluency: a spherical deconvolution study

Altered hemispheric lateralization of white matter pathways in developmental dyslexia: Evidence from spherical deconvolution tractography.

This study examines the structural integrity and the hemispheric lateralization patterns of four major association fiber pathways in a group of French dyslexic children and age-matched controls (from 9 to 14 years), using high angular diffusion imaging combined with spherical deconvolution tractography. Compared with age-matched controls, dyslexic children show increased hindrance-modulated ori...

White matter and visuospatial processing in autism: a constrained spherical deconvolution tractography study.

Autism spectrum disorders (ASDs) are associated with a marked disturbance of neural functional connectivity, which may arise from disrupted organization of white matter. The aim of this study was to use constrained spherical deconvolution (CSD)-based tractography to isolate and characterize major intrahemispheric white matter tracts that are important in visuospatial processing. CSD-based tract...

Competing physiological pathways link individual differences in weight and abdominal adiposity to white matter microstructure

Being overweight or obese is associated with reduced white matter integrity throughout the brain. It is not yet clear which physiological systems mediate the association between inter-individual variation in adiposity and white matter. We tested whether composite indicators of cardiovascular, lipid, glucose, and inflammatory factors would mediate the adiposity-related variation in white matter ...

Pathways from Adiposity to White Matter Microstructure Competing Physiological Pathways Link Individual Differences in Weight and Abdominal Adiposity to White Matter Microstructure

Improved Sensitivity to Cerebral White Matter Abnormalities in Alzheimer’s Disease with Spherical Deconvolution Based Tractography

Diffusion tensor imaging (DTI) based fiber tractography (FT) is the most popular approach for investigating white matter tracts in vivo, despite its inability to reconstruct fiber pathways in regions with "crossing fibers." Recently, constrained spherical deconvolution (CSD) has been developed to mitigate the adverse effects of "crossing fibers" on DTI based FT. Notwithstanding the methodologic...